Federal government websites often end in. The site is secure. Preview improvements coming to the PMC website in October Learn More or Try it out now. The authors may share de-identified data that underlie the results reported in this article.
Data will be available upon receipt of a request detailing the study hypothesis and statistical analysis plan. All requests should be sent to the corresponding authors. The steering committee of this study will discuss all requests and decide based on the novelty and scientific rigor of the proposal whether data sharing is appropriate. All applicants will be asked to sign a data access agreement. Participants were recruited from a population-based health plan in Barcelona, Spain, and from a convenience sample recruited via services for people with intellectual disabilities in England and Scotland.
Our work revealed similar prevalence, age at diagnosis and Cambridge Cognitive Examination for Older Adults with Down Syndrome scores by sex, but males showed lower modified cued recall test scores from age 45 compared with females.
AT N biomarkers were comparable in males and females. This difference was not seen in males Accounting for, reporting and publishing sex-stratified data, even when no sex differences are found, is central to helping advance precision medicine. Iulita et al. Accounting for and reporting sex-stratified data, even when no significant differences are found, is central to developing precision medicine. The topic of sex differences is now positioned as a top priority in neurology and translational neuroscience research, particularly in the context of precision medicine and personalized care strategies.
While some biomarkers might not differ by sex, certain risk factors can impact males and females differently. We used biochemical and neuroimaging measures to assess amyloid A , tau T and neurodegeneration N biomarkers across age and sex.
